| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 12/09/25 02:15 | Green Bay Packers | Washington Commanders | 27-18 |
| 14/09/25 19:00 | Detroit Lions | Chicago Bears | --- |
| 14/09/25 19:00 | Cincinnati Bengals | Jacksonville Jaguars | --- |
| 14/09/25 19:00 | Dallas Cowboys | New York Giants | --- |
| 14/09/25 19:00 | New Orleans Saints | San Francisco 49ers | --- |
| 14/09/25 19:00 | Baltimore Ravens | Cleveland Browns | --- |
| 14/09/25 19:00 | Tennessee Titans | Los Angeles Rams | --- |
| 14/09/25 19:00 | Pittsburgh Steelers | Seattle Seahawks | --- |
| 14/09/25 19:00 | New York Jets | Buffalo Bills | --- |
| 14/09/25 19:00 | Miami Dolphins | New England Patriots | --- |
| 14/09/25 22:05 | Indianapolis Colts | Denver Broncos | --- |
| 14/09/25 22:05 | Arizona Cardinals | Carolina Panthers | --- |
| 14/09/25 22:25 | Kansas City Chiefs | Philadelphia Eagles | --- |
| 15/09/25 02:20 | Minnesota Vikings | Atlanta Falcons | --- |
| 16/09/25 01:00 | Houston Texans | Tampa Bay Buccaneers | --- |
| 16/09/25 04:00 | Las Vegas Raiders | Los Angeles Chargers | --- |